Resetting the Brain with Magic Mushrooms to Cure Long-Term Depression and PTSD in 2022

Long-term depression can be difficult to treat with traditional methods. But more and more people suffering from serious depression, such as PTSD as a result of military duty, are having success with magic mushrooms through psilocybin treatment. Magic mushrooms don’t just alleviate symptoms temporarily, but can actually reset the brain, effectively curing depression.

In this article we examine how magic mushrooms do this, but first let’s look at why long-term depression is so hard to treat.

Depression Can Physically Change Your Brain

While research is still being conducted, it does appear that depression, especially long-term depression can actually modify the structure of the brain. Long-term depression can decrease the gray matter volume and synapses of some parts of the brain, particularly the hippocampus and the prefrontal cortex while increasing the size of the amygdala. — the area of the brain that controls fear. The hippocampus is sensitive to emotions and stress hormones which can affect learning and memory. The prefrontal cortex enables higher level thinking and planning. Depression also seems to elevate inflammation in the brain which can lead to a whole host of problems such as the destruction of brain cells and accelerating brain aging.

These drastic changes are more pronounced with long-term depression and may be one of the reasons long-term depression can be very difficult to treat with conventional treatments such as talk therapy or even antidepressant drugs that modify brain chemicals and circuitry.

The Magic of Magic Mushrooms to Reset the Brain

Wouldn’t it be great if there was a safe, FDA-approved treatment that could actually restructure the depressed brain, returning it to a healthy state? Enter magic mushrooms and their magic psychedelic component: psilocybin. Back in 2019, psilocybin and its active element, psilocin, were recognized for their potential to treat depression and were given breakthrough therapy designation by the US Food and Drug Administration.

As a bonus, the positive effects of magic mushrooms are immediate, unlike anti-depressants that can take 6 to 8 weeks to work. And even better, the effects are long lasting — so much so that 54% of the participants in the above study were considered to be in remission after four weeks, since they had no remaining symptoms of depression at all.

Study: Magic Mushrooms are Four Times More Effective at Treating Depression than Anti-Depressants

One study out of Johns Hopkins found that Magic Mushrooms were four times more effective than antidepressants at treating long-term depression. As a bonus, the positive effects of magic mushrooms are immediate, unlike anti-depressants that can take 6 to 8 weeks to work. And even better, the effects are long lasting — so much so that 54% of the participants in the above study were considered to be in remission after four weeks, since they had no remaining symptoms of depression at all.

As a bonus, the positive effects of magic mushrooms are immediate, unlike anti-depressants that can take 6 to 8 weeks to work. And even better, the effects are long lasting — so much so that 54% of the participants in the above study were considered to be in remission after four weeks, since they had no remaining symptoms of depression at all.

These studies showing the effectiveness of magic mushrooms for depression didn’t delve into how magic mushrooms accomplished their magic. More research needs to be done, but recent studies have shown that magic mushrooms can remodel connections in the brain for a lasting effect.

How Psilocybin Performs its Magic

In one 2021 study, a single dose of psilocybin led to a 10% increase in robust, neuronal connections in mice. This study focused on the microscopic brain connections (dendrites) in the prefrontal cortex. Dendrites are highly plastic, meaning they grow or shrink in response to neurological changes. Using imaging techniques, the researchers found that about one third of the connections that were created soon after dosing, remained intact after about a month.

Another study looked at whole-brained networks, meaning all the neurons in the brain as well as the activity of the neurotransmitters that carry messages between the neurons. The study suggests that psilocybin destabilizes the habitual neural pathways in the brain, allowing for new routes and networks. Under the influence of psilocybin, the brain creates a feedback loop of neuron activity and neurotransmitter release that allows a new network to develop. The result is a healthier neurological response to life.

Psilocybin Offers Fantastic Hope For Those Suffering from Depression

These new psilocybin studies offer fantastic hope for people suffering from long-term, debilitating depression. If this applies to you, and you wish to try them for mental health purposes, please do so under the supervision of trained drug facilitators.

If you’d like to explore the world of magic mushrooms available, our Canadian friends are invited to visit our online shop.